Paolo Manunta Selected Research

adducin

1/2020	Hypertension in High School Students: Genetic and Environmental Factors: The HYGEF Study.
12/2015	Beta-adducin and sodium-calcium exchanger 1 gene variants are associated with systemic lupus erythematosus and lupus nephritis.
11/2014	Rostafuroxin protects from podocyte injury and proteinuria induced by adducin genetic variants and ouabain.
1/2011	Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
12/2010	Genetics of primary hypertension: the clinical impact of adducin polymorphisms.
11/2010	Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.
2/2010	alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy.
9/2008	Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome.
5/2008	Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension.
5/2007	Adducin polymorphisms and the treatment of hypertension.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Paolo Manunta Research Topics

Disease

38	Hypertension (High Blood Pressure) 01/2022 - 10/2004
19	Essential Hypertension 01/2021 - 12/2002
4	Chronic Renal Insufficiency 01/2022 - 12/2013
3	Chronic Kidney Failure (Chronic Renal Failure) 06/2022 - 05/2015
3	COVID-19 01/2022 - 01/2021
3	Inflammation (Inflammations) 11/2020 - 12/2015
3	Proteinuria 01/2019 - 02/2010
3	Renal Insufficiency (Renal Failure) 07/2018 - 01/2009
3	Hypertrophy 09/2012 - 09/2005
3	Myocardial Infarction 05/2007 - 01/2004
3	Stroke (Strokes) 05/2007 - 01/2004
2	Sarcopenia 06/2022 - 11/2020
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2022 - 12/2013
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2018 - 12/2015
2	Reperfusion Injury 07/2018 - 10/2016
2	Disease Progression 07/2018 - 11/2014
2	Heart Failure 01/2015 - 03/2006
2	Acute Kidney Injury (Acute Renal Failure) 09/2014 - 03/2013
1	Frailty 06/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2022
1	Infections 01/2022
1	Atrophy 11/2020
1	Atherosclerosis 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2019
1	Nervous System Diseases (Neurological Disorders) 12/2018
1	Kidney Calculi (Kidney Stone) 10/2018
1	Autism Spectrum Disorder 10/2018
1	Brain Diseases (Brain Disorder) 10/2018
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 07/2018
1	Autosomal Dominant Polycystic Kidney (ADPKD) 07/2018
1	Nephrolithiasis 01/2018
1	Migraine Disorders (Migraine) 02/2017
1	Exfoliation Syndrome 01/2017
1	Neoplasms (Cancer) 01/2017
1	Glaucoma 01/2017
1	Renal Cell Carcinoma (Grawitz Tumor) 11/2016
1	Pathologic Processes 11/2016

Drug/Important Bio-Agent (IBA)

25	Ouabain (G Strophanthin)IBA 01/2019 - 09/2005
16	adducinIBA 01/2020 - 03/2003
15	SodiumIBA 01/2020 - 03/2003
13	SaltsIBA 01/2020 - 03/2006
9	Pharmaceutical PreparationsIBA 01/2022 - 01/2004
9	Antihypertensive Agents (Antihypertensives)IBA 01/2021 - 01/2004
6	Proteins (Proteins, Gene)FDA Link 02/2017 - 01/2007
5	Biological ProductsIBA 01/2022 - 11/2010
5	rostafuroxinIBA 01/2021 - 09/2005
5	Adenosine Triphosphatases (ATPase)IBA 10/2018 - 10/2005
5	DiureticsIBA 01/2017 - 03/2003
4	CalciumIBA 10/2018 - 03/2006
4	AldosteroneIBA 10/2016 - 03/2006
4	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 06/2015 - 03/2003
3	Biomarkers (Surrogate Marker)IBA 11/2016 - 03/2013
3	Hormones (Hormone)IBA 10/2016 - 09/2012
3	Cardiac GlycosidesIBA 05/2015 - 03/2006
2	CreatinineIBA 01/2022 - 01/2019
2	AlbuminsIBA 01/2019 - 12/2013
2	TRPC6 Cation ChannelIBA 12/2018 - 07/2018
2	PotassiumIBA 10/2018 - 10/2005
2	Matrix Gla ProteinIBA 01/2018 - 02/2015
2	Transcription Factors (Transcription Factor)IBA 01/2017 - 11/2013
2	Vasoconstrictor AgentsIBA 10/2016 - 03/2006
2	Diltiazem (Cardizem)FDA LinkGeneric 06/2015 - 08/2013
2	UromodulinIBA 12/2014 - 12/2013
2	nephrinIBA 12/2014 - 11/2014
2	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 08/2013 - 11/2011
2	SteroidsIBA 09/2012 - 04/2009
2	Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA 12/2010 - 01/2009
2	Sodium-Calcium ExchangerIBA 12/2010 - 03/2006
1	Inositol PhosphatesIBA 01/2022
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Indicators and Reagents (Reagents)IBA 01/2022
1	HDL CholesterolIBA 01/2022
1	Losartan (Cozaar)FDA LinkGeneric 01/2021
1	CytokinesIBA 11/2020
1	Etanercept (Enbrel)FDA Link 11/2020
1	Interleukin-6 (Interleukin 6)IBA 11/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020
1	Saline SolutionIBA 01/2020
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2019
1	Valsartan (Vals)FDA Link 01/2019
1	benazepril (Briem)FDA LinkGeneric 01/2019
1	Angiotensin Receptor AntagonistsIBA 01/2019
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2019
1	Sodium Chloride FDA LinkGeneric 10/2018
1	claudin 14IBA 10/2018
1	EnzymesIBA 10/2018
1	Ion Channels (Ion Channel)IBA 07/2018
1	Tolvaptan FDA Link 07/2018
1	Vitamin K FDA Link 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 02/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2017
1	MicroRNAs (MicroRNA)IBA 11/2016

Therapy/Procedure

12	Therapeutics 06/2021 - 03/2003
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2022 - 07/2018
2	Renal Dialysis (Hemodialysis) 01/2022 - 06/2021
2	Nephrectomy 11/2016 - 10/2016
1	Polypharmacy 06/2022
1	Subcutaneous Injections 11/2020